Restylane Defyne

Define your look from every angle

Restylane Defyne is a hyaluronic acid (HA) filler that helps to soften deep laugh lines, such as nasolabial folds, and can be used to define the shape of the chin. Restylane Defyne can correct mild-to-moderate chin retrusion, with 98% of patients having improved double chin appearance after treatment.

Dynamic support

Restylane Defyne is designed to help support your facial expressions—for natural-looking results that help maintain your natural facial movement.

Bring your look into proportion

Minimally invasive chin augmentation with Restylane Defyne can bring balance to the profile with correction of a “weak chin,” in addition to improving the appearance of facial symmetry.

Real people. Real results.


of patients had improved facial harmony after treatment with Restylane Defyne.


of patients had improved double chin appearance after treatment with Restylane Defyne.


of patients reported feeling satisfied with their facial symmetry after treatment.


of patients reported feeling satisfied with how balanced their face looked after treatment.

Frequently Asked Questions

The Restylane family of products is a brand of hyaluronic acid (HA) dermal fillers designed for natural-looking results. Each product is a clear gel formulation of HA specifically formulated to act like your body's own naturally produced HA. Each Restylane product is designed for a specific purpose. The portfolio includes Restylane, Restylane-L, Restylane Lyft, Restylane Silk, Restylane Kysse, Restylane Refyne, Restylane Defyne, Restylane Contour, and Restylane Eyelight. Restylane products are indicated only for patients over the age of 21.
Results from treatment with Restylane Defyne have been shown to last up to 1 year for facial wrinkles and folds, like nasolabial folds and marionette lines, as well as the chin.
Common side effects can include swelling, redness, pain, bruising, headache, tenderness, lump formation, itching at the injection site, and impaired hand function. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 to 18 days in the lips.
Restylane products should not be used by people who are pregnant, breastfeeding, or under 22 years of age, have recently used drugs that thin the blood or prevent clotting, have had previous bad allergies, have serious allergies to drugs that have previously required in-hospital treatment, have bleeding disorders, or have a known allergy to lidocaine.
Chin filler is used for minimally invasive augmentation of the chin to improve the chin’s projection or shape. Restylane Defyne can be used to reduce the appearance of a double chin or correct mild-to-moderate chin retrusion.
Swelling from chin filler with Restylane Defyne typically lasts between 1 and 7 days.
The amount of chin filler used will vary. For augmentation to improve the chin profile, the maximum recommended injected volume per patient and treatment is 4 mL.
Chin filler can augment the chin projection, lessening the appearance of roundness and resulting in a more heart- or oval-shaped appearance. Restylane Defyne can also reduce the appearance of a double chin.
Side effects at the injection site for Restylane Defyne in the chin included swelling, small bumps, redness, pain, tenderness, bruising, and itching, mainly mild to moderate reactions that disappeared within 1 to 2 weeks.
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